1326-1350 of 1502 Resource Library
1326-1350 of 1502 Resource Library
APPLICATION NOTE
Introduction Vitamins are involved in a variety of different physiological processes and must be assimilated with the daily nutrition as they cannot be synthesized within the human body. The biochemical functions of vitamin C (ascorbic acid) are mainly …
APPLICATION NOTE
Introduction Organic solvents are commonly used in the production of active pharmaceutical ingredients (API) and pharmaceutical products. The solvents are used for varying purposes including as synthesis reaction media, in the separation and …
APPLICATION NOTE
Introduction There are many types of nanocomposites - such as epoxy, polymer, and carbon tube materials. Nanocomposites are made from embedding materials into one another with at least one of the phases showing dimensions in the nanometer range. This …
APPLICATION NOTE
Introduction USP 467 is a widely used method for the determination of residual solvents in pharmaceutical products using gas chromatography (GC) with a flame ionization detector (FID). Due to the prescribed GC method settings, USP 467 has a long run …
APPLICATION NOTE
Introduction When CASE chemicals like coatings and paints are formulated, pigments, binding agents, and additives are dissolved into a carrier solvent, often a volatile organic compound (VOC) or water. This solvent functions to lower the mixture’s …
APPLICATION NOTE
Introduction There are a wide variety of characterization techniques which may be used to identify drugs of abuse, including infrared spectroscopy, Raman spectroscopy, mass spectrometry, gas chromatography, x-ray diffractometry, immunoassays and urine …
APPLICATION NOTE
Introduction The sale of alcoholic beverages is regulated and taxed differently than non-alcoholic ones. Other food products, such as fruits and sauces, may contain alcohol as well from natural fermentation. This application note will expand upon the …
APPLICATION NOTE
Introduction Fats and oils are used in cooking as a frying medium or as an ingredient in baking. Autoxidation of lipids in the fats and oils proceeds as a free-radical chain reaction that leads to rancidity causing foul flavors and smells. Phenolic …
APPLICATION NOTE
Introduction Histamine is a naturally occurring contaminant that can be found in improperly handled seafood. Quality tuna has histamine levels below 50 ppm and high levels of histamine in seafood can cause scombroid food poisoning. Scombroid poisoning …
APPLICATION NOTE
Introduction Acrylate polymers are utilized for a host of applications due to their varied physical properties and ease of synthesis. These acrylates are sought after specifically for coatings, adhesives, sealants and elastomers (CASE) applications …
APPLICATION NOTE
Introduction Urea is a white, crystalline solid containing 46% nitrogen. Due to its high nitrogen content, urea is the most widely used source of nitrogen for nitrogen-based fertilizers worldwide. The accurate determination of urea in urea-based …
APPLICATION NOTE
Introduction Different types of plastics are used for these diverse applications, but all plastic manufacturing has a few common raw material needs, including monomers and solvents. Plastic manufacturing workflows are designed to use all monomer input …
APPLICATION NOTE
Introduction Cetyl alcohol, also known as palmityl alcohol or 1-hexadecanol, is a long-chain aliphatic alcohol that is a common additive in foods, cosmetics, personal care products (e.g., lotions and creams), and industrial fuels. To ensure cetyl …
APPLICATION NOTE
Introduction The recent emergence of mRNA-based vaccines and therapies has made clear the need for reliable analytical methods that can successfully identify, characterize, and quantify mRNA. This chemical instability demands a deeper understanding of …
APPLICATION NOTE
Introduction At the height of the first wave of the COVID-19 pandemic, consumers around the world experienced a supply shortage related to alcohol-based hand sanitizer. As new producers entered the market, and existing manufacturers sought to ramp-up …
APPLICATION NOTE
Introduction This Application Brief demonstrates the ability of PerkinElmer's LC 300 instrument platform, and SimplicityChrom™ chromatographic data system (CDS) software to successfully meet the United States Pharmacopeia (USP) performance requirements …
APPLICATION NOTE
DS2 Automation of MaxSignal® Histamine Enzymatic Assay Introduction The MaxSignal® Histamine Enzymatic Assay is a colorimetric enzymatic assay for the determination of histamine in fresh fish/seafood (AOAC-validated), fish meal, wine, and milk. Histamine …
APPLICATION NOTE
Introduction Polyacrylic acid, also known as Carbomer, is used extensively in formulations across many industries, including cosmetics, pharmaceuticals, and personal care. Carbomers are polymers of acrylic acid cross-linked with allyl ethers of …
APPLICATION NOTE
Introduction Almost 400 million tons of plastics are produced every year. Unfortunately, this problem is only going to grow because with an estimated mass of 5 billion tons of plastic in landfill and the environment that will break down over time it …
APPLICATION NOTE
Introduction Ethylene glycol and diethylene glycol are considered toxic to human health and both are commonly present as impurities in propylene glycol. In response to these toxic considerations and adhering to the recommendations from US Food and Drug …
APPLICATION NOTE
Introduction The production of vehicles running high-ethanol-content gasoline blends, known as flex fuels, has increased. Such fuels have garnered attention due to their reduction in greenhouse gas emissions as well as their reduced volatility/vapor …
APPLICATION NOTE
Introduction DEF is a colorless liquid which is beneficial in the reduction of nitrogen oxide (NOx) emissions from diesel engines. The Selective Catalytic Reduction (SCR) system injects the DEF through a catalyst, converting the harmful nitrogen oxides …
APPLICATION NOTE
Introduction This application note describes a simple experiment on an amorphous polymer. PEEK (polyetheretherketone) is a common polymeric material used for a variety of applications. PEEK is a high-performance semicrystalline thermoplastic with …
APPLICATION NOTE
Introduction Aluminium salts such as potassium aluminium sulphate, aluminium phosphate and aluminium oxyhydroxide have been extensively used as adjuvants in licensed vaccines. As active ingredients, quantification of aluminium salts in vaccine …
ARTICLE
Introduction Quality assurance and quality control are key components of every pharmaceutical manufacturing. To meet the standards set by U.S. Pharmacopeia (USP) <232> and the International Council for Harmonization (ICH) Q3D, QA/QC labs performing …