Introduction
Per- and polyfluoroalkyl substances (PFAS) are a group of man-made chemicals that have been used in a wide variety of industries around the world since the 1950s. Applications include food packaging, various household products, fire-suppression foams, and water-repellent clothing. This class of chemicals is incredibly stable, so they are persistent and accumulate in the environment.
As of March 2023, the EPA has announced the proposed National Primary Drinking Water Regulation (NPDWR) where public water systems must monitor for six PFAS analytes. The enforceable levels have also been published as guidance. To allow current and future water labs to meet the proposed regulatory levels, and meet faster sample turnaround times, the following session will provide an overview on the new EPA Proposed PFAS National Primary Drinking Water Regulation and validation of PerkinElmer’s method for the six PFAS compound. Specifics include discussion, and data, on the most economical sample preparation steps, selecting the appropriate internal standards, QSight LC/MS-MS mass spectrometry setup and analysis, and Simplicity 3Q data interpretation.
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