Introduction
Hemodialysis is a procedure that’s required when kidneys are damaged and cannot fully perform their function, during which blood is pumped from the body through a machine where it is cleaned and waste removed before returning the cleaned blood back to the body. The washing solution which removes the waste is called a hemodialysis solution. Patients undergoing dialysis are usually exposed to significant amounts of this solution on a regular basis. Plus, its components and their concentrations can vary depending on the needs of the patient. With so much exposure and variations in make-up, the composition of the hemodialysis solutions is critical and must be tightly controlled.
Major components of hemodialysis solutions include calcium (Ca), magnesium (Mg), potassium (K), and sodium (Na). These elements have been defined by monographs in pharmaceutical products and need to abide by very stringent control limits.
This work demonstrates the ability of the Avio® 550 Max fully simultaneous ICP-OES to provide accurate, repeatable analyses of major components in hemodialysis solutions, meeting the tight tolerances required.
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