Redefining LC Versatility Maximizing Lab Trust
For laboratories looking to achieve the highest levels of versatility without compromising on productivity, the LC 300 HPLC and UHPLC Systems deliver the flexibility, performance, and efficiency you need for even the most challenging analytical demands. With fully customizable detectors and accessories, each LC 300 HPLC and UHPLC System is intuitive and designed to meet high-throughput lab requirements, with no additional burden on lab staff. The PerkinElmer SimplicityChrom™ CDS Software manages the complete workflow and with the LC 300 HPLC and UHPLC System delivers an innovative user experience with intuitive functions and automated processes.
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The LC 300 HPLC and UHPLC System integrate the components seamlessly, to deliver the dependability, power, and efficiency you need to achieve your goals. Whether analyzing food samples for label-claim accuracy, or pharmaceuticals and consumer goods for potential impurities, the LC 300 HPLC and UHPLC System complemented by SimplicityChrom CDS Software, not only fulfills your current requirements but also evolves with your growing needs.

Click on the tab sections below to learn more about each component.

A robust, precise autosampler is necessary to achieve optimal efficiency and accuracy.
- Advanced fluidics technology featuring a patented injection valve that facilitates accurate and highly reproducible injections
- Integrated column oven
- Onboard, automated dilution and derivatization, without the use of additional hardware or software
- High-visibility color LCD screen for quick and efficient review of pump pressure, oven and sample tray temperature, and sample queue status without having to log into your CDS software

A robust, precise autosampler is necessary to achieve optimal efficiency and accuracy.
- Advanced fluidics technology featuring a patented injection valve that facilitates accurate and highly reproducible injections
- Integrated column oven
- Onboard, automated dilution and derivatization, without the use of additional hardware or software
- High-visibility color LCD screen for quick and efficient review of pump pressure, oven and sample tray temperature, and sample queue status without having to log into your CDS software

- Standard reciprocating LC 300 pump utilizes an advanced implementation of a rugged linear drive to deliver ultraprecise gradient flows
- Four individually motor-driven and -controlled pump heads, generating maximum freedom for precise flow control and pulsation reduction
- Self-cleaning, active-seal wash system ensuring you achieve maximum life of the piston seals
- Efficient software-controlled prime and purge completed in just minutes

- Ultimate flexibility to achieve your analytical goals with a large column compartment that can accommodate columns measuring up to 30 cm in length
- Precise and consistent temperature control from 5 °C to 90 °C, ensuring accurate and repeatable analyses
- Pairing SimplicityChrom CDS Software with an optional internal column selection valve for automated column switching of up to six columns, saving time and increasing efficiency

High-sensitivity detection is essential for most LC applications. LC 300 HPLC and UHPLC Systems can be configured with one or more detectors to meet the needs of your laboratory. And with upgrade options available, your investment is future-proofed as your analytical needs grow or change. Each LC 300 HPLC and UHPLC System detectors features an integrated solvent and waste-tubing management system, and the PDA and two UV/Vis detectors also feature a built-in solvent organizer to reduce the number of modules in the LC stack while simplifying asset-management.
Resources

LC 300 HPLC and UHPLC Systems Interactive Brochure
For laboratories looking to achieve the highest levels of versatility without compromising on productivity, the LC 300 HPLC and UHPLC Systems deliver the flexib ...
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How to Guide for HPLC: Choosing the Right Detector
For laboratories looking to achieve the highest levels of versatility without compromising on productivity, the LC 300 HPLC and UHPLC Systems deliver the flexib ...

PerkinElmer LC 300 Autosampler Intermediate Loop Decompression (ILD) Injection Valve
The injection of an accurate and reproducible sample volume into a UHPLC system is challenging, but essential to ensuring a high quality analysis. The patented ...
Technologies
Explore our Applications

Analysis of Phytoestrogen Isoflavones in Dietary Supplements by HPLC/UV
Isoflavones are water-soluble compounds found in many plant and food sources. Designated as phytoestrogens, isoflavones are structurally similar to to the femal ...

Analysis of Sugars in Maple Syrup by HILIC with Refractive Index Detection
Maple syrup, a common natural sweetener, is consumed regularly by households around the world. Quantification of sugar content in maple syrup is paramount to sa ...

Analysis of Common Preservatives in Personal Care Products by HPLC with UV Detection
Parabens are utilized as an antimicrobial preservative in many commercial offerings including cosmetics, personal care products and foods, and offer both chemic ...
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Columns - Liquid Chromatography
A comprehensive selection of HPLC, UHPLC and SFC column chemistries on traditional silica ensure that you have the optimum column for your application. High per ...
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Laboratory Services
A comprehensive selection of HPLC, UHPLC and SFC column chemistries on traditional silica ensure that you have the optimum column for your application. High per ...