Introduction
Inductively coupled plasma mass spectrometry (ICP-MS) has become the preferred method for detecting trace-level amounts of elements like lead, arsenic, mercury, and copper in bodily fluids such as urine, blood, saliva, and tissue. However, analyzing trace elements in urine using ICP-MS presents a challenge, given the complex composition of the matrix.
However, thanks to the proprietary design of the NexION® 5000 multi-quadrupole ICP-MS, by employing a simple dilution of the urine samples with a suitable diluent, it is possible to measure panels or individual analytes quickly and accurately in the urine matrix, without upstream digestion of the samples. Read this application note to learn more.